PDGFRA antibody (Platelet-Derived Growth Factor Receptor, alpha Polypeptide) (AA 350-400)

Details for Product anti-PDGFRA Antibody No. ABIN6944464
Antigen
  • AI115593
  • CD140a
  • Pdgfr-2
  • APDGFR
  • PDGFACE
  • CD140A
  • PDGFR-2
  • PDGFR2
  • RHEPDGFRA
  • PDGFR
  • PDGFR-A
  • platelet derived growth factor receptor alpha
  • platelet derived growth factor receptor, alpha polypeptide
  • platelet-derived growth factor receptor, alpha polypeptide L homeolog
  • platelet-derived growth factor receptor, alpha polypeptide
  • PDGFRA
  • Pdgfra
  • pdgfra.L
Epitope
AA 350-400
35
28
28
25
19
19
17
16
15
15
15
15
13
11
10
10
10
10
8
8
7
7
6
5
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
492
284
238
6
6
6
5
5
3
3
3
2
2
1
1
1
1
Host
Rabbit
424
92
5
1
1
Clonality
Polyclonal
Conjugate
This PDGFRA antibody is un-conjugated
36
26
25
24
23
14
12
12
12
12
12
12
5
5
5
5
5
1
1
Application
Western Blotting (WB)
302
206
163
80
69
58
39
31
14
14
12
9
4
3
3
2
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PDGFRA
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PDGFRA products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PDGFRA (PDGFRA Antibody Abstract)
Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]

Subcellular location: Extracellular


Synonyms: PDGF Receptor alpha, Platelet-dirived growth factor receptor-alpha, Alpha platelet derived growth factor receptor, CD 140a, CD140a, CD140a antigen, MGC74795, PDGF alpha chain, PDGF R alpha, PDGFR 2, PDGFR A, PDGFR alpha, PDGFR2, PDGFRA, Platelet derived growth factor receptor 2, Platelet derived growth factor receptor alpha, Platelet derived growth factor receptor alpha polypeptide, PGFRA_HUMAN.
Gene ID 5156
UniProt P16234
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
Application Notes WB(1:500-2000)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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