PDGFRA (Tyr720) (pTyr720) antibody (HRP)

Details for Product No. ABIN6944467
Antigen
Epitope
pTyr720
8
Reactivity
Human, Mouse (Murine), Rat (Rattus)
8
8
8
Host
Rabbit
8
Clonality
Polyclonal
Conjugate
HRP
3
2
Application
Western Blotting (WB)
8
Options
Immunogen KLH conjugated synthesised phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr720
Isotype IgG
Purification Purified by Protein A.
Antigen
Background

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]


Synonyms: PDGF Receptor alpha (phospho Y720), p-PDGF Receptor alpha (phospho Y720), Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, MGC74795, PDGF alpha chain, PDGF-R-alpha, PDGFR 2, PDGFR alpha, PDGFR2, PDGFRA, PDGFRA/BCR fusion, PGFRA_HUMAN, Platelet derived growth factor receptor 2, Platelet derived growth factor receptor alpha, Platelet derived growth factor receptor alpha polypeptide, Platelet derived growth factor receptor, Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein, RHEPDGFRA.
Gene ID 5156
UniProt P16234
Application Notes WB(1:300-1000)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months