PPARGC1B antibody (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta) (Alexa Fluor 750)

Details for Product anti-PPARGC1B Antibody No. ABIN6944542
Target
Reactivity
Cow, Dog, Human, Mouse, Pig, Rat
38
23
17
14
14
14
12
6
4
4
4
4
Host
Rabbit
34
3
1
Clonality
Polyclonal
Conjugate
This PPARGC1B antibody is conjugated to Alexa Fluor 750
4
4
3
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
16
15
7
6
4
3
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PGC1 beta
Isotype IgG
Purification Purified by Protein A.
Target
Alternative Name PGC1 beta (PPARGC1B Antibody Abstract)
Background

Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle.


Synonyms: PERC, peroxisome prolerative activated receptor, gamma, coactivator 1, peroxisome prolerator-activated receptor gamma coactivator 1 beta, Peroxisome prolerator-activated receptor gamma coactivator 1-beta, peroxisome prolerator-activated receptor gamma, coactivator 1 beta, PGC-1beta, PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1, Ppargc1b, PRGC2_HUMAN.
Gene ID 133522
Pathways AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Application Notes IF(IHC-P)(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months