PPARGC1B antibody (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta)

Details for Product anti-PPARGC1B Antibody No. ABIN6944648
Antigen
  • PPARGC1B
  • 4631412G21Rik
  • Perc
  • PGC1beta
  • ERRL1
  • PERC
  • PGC-1(beta)
  • PGC1B
  • PPARG coactivator 1 beta
  • peroxisome proliferative activated receptor, gamma, coactivator 1 beta
  • PPARGC1B
  • Ppargc1b
Reactivity
Human, Rat (Rattus)
52
30
24
19
19
19
12
Host
Rabbit
47
4
1
Clonality (Clone)
Monoclonal ()
Conjugate
This PPARGC1B antibody is un-conjugated
5
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
17
15
9
5
4
3
3
Options
Immunogen Recombinant protein within C-terminal human PGC1 beta
Clone 6H5
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PPARGC1B products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PPARGC1B (PPARGC1B Antibody Abstract)
Background

Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Subcellular location: Nucleus


Synonyms: Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1.
Gene ID 133522
UniProt Q86YN6
Pathways AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Application Notes WB(1:500-2000), FCM(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Did you look for something else?