Reelin antibody
Quick Overview for Reelin antibody (ABIN6944773)
Target
See all Reelin (RELN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Cross-Reactivity
- Human, Mouse, Rat
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Purification
- Purified by Protein A.
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Immunogen
- Human Reelin aa 241-340
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Isotype
- IgG
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Application Notes
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WB 1:300-5000
IHC-P 1:200-400 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 12 months
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- Reelin (RELN)
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Alternative Name
- Reelin
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Background
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Synonyms: Reelin, RELN
Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
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Gene ID
- 5649
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UniProt
- P78509
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Pathways
- Synaptic Membrane
Target
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