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Reelin antibody

The Rabbit Monoclonal anti-Reelin antibody has been validated for WB and IHC (p). It is suitable to detect Reelin in samples from Human, Rat and Mouse.
Catalog No. ABIN6944773

Quick Overview for Reelin antibody (ABIN6944773)

Target

See all Reelin (RELN) Antibodies
Reelin (RELN)

Reactivity

Human, Rat, Mouse

Host

  • 51
  • 22
  • 2
  • 1
Rabbit

Clonality

  • 44
  • 32
Monoclonal

Conjugate

  • 52
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This Reelin antibody is un-conjugated

Application

  • 56
  • 49
  • 37
  • 35
  • 13
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

4C3
  • Cross-Reactivity

    Human, Mouse, Rat

    Purification

    Purified by Protein A.

    Immunogen

    Human Reelin aa 241-340

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    IHC-P 1:200-400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Reelin (RELN)

    Alternative Name

    Reelin

    Background

    Synonyms: Reelin, RELN

    Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

    Gene ID

    5649

    UniProt

    P78509

    Pathways

    Synaptic Membrane
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