TTC37 antibody

Catalog No. ABIN6944888

This anti-TTC37 antibody is a Rabbit Polyclonal antibody detecting TTC37 in WB, IF and IF (cc). Suitable for Human.

Quick Overview for TTC37 antibody (ABIN6944888)

Target: TTC37 (Tetratricopeptide Repeat Domain 37 (TTC37))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC37 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-TTC37 Antibody

Cross-Reactivity: Human

Purification: Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300

Immunogen: Polyclonal antibody raised in rabbit against human SKI3, using a recombinant protein

Application Details

Application Notes: WB 1:300-5000
IF(ICC) 1:50-200
IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 3 μg/μL

Buffer: PBS with 0.05 % sodium azide and 0.05 % Proclin300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TTC37

Target: TTC37 (Tetratricopeptide Repeat Domain 37 (TTC37))

Alternative Name: Ski3

Background:

Synonyms: Antiviral protein SKI8, SKI8, Superkiller protein 8, REC103

Background: Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes. Also component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology.

Gene ID: 852659

UniProt: Q02793