TNP1 antibody (AA 201-300)

Catalog No. ABIN6945217

The Rabbit Polyclonal anti-TNP1 antibody has been validated for WB, ELISA, IF (cc), IF (p), ICC, IHC (p) and IHC (fro). It is suitable to detect TNP1 in samples from Human.

Quick Overview for TNP1 antibody (AA 201-300) (ABIN6945217)

Target: TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TNP1 Antibody

Binding Specificity: AA 201-300

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Transition Protein 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TNP1

Target: TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))

Alternative Name: Transition Protein 1

Background:

Synonyms: 551G9.2, Anti Eukaryotic Release Factor 3a, Anti G1 to S phase transition 1, Anti GST1, homolog of yeast, eRF 3a, eRF3a, G1 to S phase transition 1, G1 to S phase transition protein 1 homolog, G1 to S phase transition protein, GSPT 1, GSPT1, GST 1, GST1, GTP binding protein GST1 HS, Transition protein 1, ERF3A_MOUSE.

Background: eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Gene ID: 14852

UniProt: P15170