VPS33B antibody (AA 361-460)
Quick Overview for VPS33B antibody (AA 361-460) (ABIN6945326)
Target
See all VPS33B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 361-460
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Cross-Reactivity
- Mouse
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Predicted Reactivity
- Human,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human VPS33B
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Isotype
- IgG
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Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))
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Alternative Name
- VPS33B
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Background
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Synonyms: FLJ14848, hVPS 33B, hVPS33B, Vacuolar protein sorting 33 homolog B (yeast), Vacuolar protein sorting 33 homolog B, Vacuolar protein sorting 33B (yeast), Vacuolar protein sorting 33B, Vacuolar protein sorting associated protein 33B, VPS 33B.
Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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Gene ID
- 608552
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UniProt
- Q9H267
Target
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