FOXA2 antibody (N-Term)

Catalog No. ABIN6952379

This Rabbit Polyclonal antibody specifically detects FOXA2 in WB, ELISA, ChIP-seq and ChIP. It exhibits reactivity toward Human.

Quick Overview for FOXA2 antibody (N-Term) (ABIN6952379)

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)

Product Details anti-FOXA2 Antibody

Binding Specificity: N-Term

Specificity: Polyclonal antibody raised in rabbit against human FOXA2 (Forkhead Box A2), using two synthetic peptides containing a sequence from the central part and the N-terminus of the protein, respectively.

Purification: Peptide affinity purified

Immunogen: synthetic peptide

Application Details

Application Notes: ChIP/ChIP-seq 2 μg:ChIP
ELISA 1:5,000
WB 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.4 μg/μL

Buffer: PBS, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for FOXA2

Target: FOXA2 (Forkhead Box A2 (FOXA2))

Alternative Name: FOXA2

Background: FOXA2 (UniProtKB/Swiss-Prot entry Q9Y261) is a member of the forkhead class of transcription factors which are involved in the transcriptional activation of liver-specific genes such as AFP, albumin, tyrosine aminotransferase, PEPCK and transthyretin. FOXA2 also plays a role glucose homeostasis and in the regulation of fat metabolism and is required for the embryonic development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs. The FOXA2 gene has been linked to sporadic cases of maturity-onset diabetes of the young.

UniProt: Q9Y261

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process