NCOR1 antibody

Catalog No. ABIN6952398

The Rabbit Polyclonal anti-NCOR1 antibody has been validated for WB, IP, ChIP and ChIP-seq. It is suitable to detect NCOR1 in samples from Human.

Quick Overview for NCOR1 antibody (ABIN6952398)

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Product Details anti-NCOR1 Antibody

Specificity: Polyclonal antibody raised in rabbit against human NCOR1 (Nuclear Receptor Corepressor 1), using a synthetic peptide containing a sequence from the central part of the protein

Cross-Reactivity: Mouse (Murine)

Purification: Affinity purified

Immunogen: synthetic peptide

Application Details

Application Notes: ChIP/ChIP-seq 2 μg:ChIP
WB 1:5,000
IP 6 μg:IP

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 μg/μL

Buffer: TBS, 0,1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Alternative Name: NCOR1

Background: NCOR1 (UniProtKB/Swiss-Prot entry O75376) mediates transcriptional repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. NCOR1 is part of a complex which may impede the access of basal transcription factors.by promoting histone deacetylation and the formation of repressive chromatin structures.

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process