CD40 antibody (APC)

Catalog No. ABIN7277985

This Mouse Monoclonal antibody specifically detects CD40 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD40 antibody (APC) (ABIN7277985)

Target: CD40

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: G28-5

Product Details anti-CD40 Antibody (APC)

Purification: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 μLper test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.

Comment:

5μl (0.25μg)/test

Restrictions: For Research Use only

Handling

Buffer: 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C protected from light

Expiry Date: 12 months

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: The G28.5 antibody reacts with human CD40, a 45-48 kDa glycoprotein that is a member of the TNF-receptor superfamily. CD40 is expressed on B cells, follicular dendritic cells, macrophages, endothelial cells, and fibroblasts. CD40 functions as a receptor for CD154 (CD40 ligand) and mediates a wide variety of immune and inflammatory responses including co-stimulation, B cell differentiation, isotype class switching, and germinal center formation.

Gene ID: 958

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints