Interleukin 17a antibody (Biotin)

Catalog No. ABIN6963908

This Mouse Monoclonal antibody specifically detects Interleukin 17a in ELISA, FACS and ELISpot. It exhibits reactivity toward Human, Cow, Pig, Dog, Sheep, Horse and Non-Human Primate and has been mentioned in 4+ publications.

Quick Overview for Interleukin 17a antibody (Biotin) (ABIN6963908)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Human, Cow, Pig, Dog, Sheep, Horse, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interleukin 17a antibody is conjugated to Biotin

Application: ELISA, Flow Cytometry (FACS), ELISpot

Clone: MT504

Product Details anti-Interleukin 17a Antibody (Biotin)

Specificity: Native and recombinant IL-17A.

Cross-Reactivity (Details): The antibody also cross-reacts with IL-17A from cow, sheep, horse, pig and dog.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-17A

Isotype: IgG1

Application Details

Application Notes: For quantification of IL-17A in solution e.g. cell culture supernatants using ELISA and for enumeration of IL-17A producing cells using ELISpot. MT504 is recommended as detection mAb in combination with coating mAb MT44.6 for human IL-17A . The antibody is also suitable for detection of IL-17A using flow cytometry.

Comment:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-Interleukin 17a antibody (Biotin) (ABIN6963908)

Behrouzi, Vaziri, Riazi Rad, Amanzadeh, Fateh, Moshiri, Khatami, Siadat: "Comparative study of pathogenic and non-pathogenic Escherichia coli outer membrane vesicles and prediction of host-interactions with TLR signaling pathways." in: BMC research notes, Vol. 11, Issue 1, pp. 539, (2019) (PubMed).

Lambracht-Washington, Fu, Frost, Rosenberg: "Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer." in: Alzheimer's research & therapy, Vol. 9, Issue 1, pp. 30, (2018) (PubMed).

Arakawa, Siewert, Stöhr, Besgen, Kim, Rühl, Nickel, Vollmer, Thomas, Krebs, Pinkert, Spannagl, Held, Kammerbauer, Besch, Dornmair, Prinz: "Melanocyte antigen triggers autoimmunity in human psoriasis." in: The Journal of experimental medicine, Vol. 212, Issue 13, pp. 2203-12, (2016) (PubMed).

Stuehler, Kuenzli, Jaeger, Baettig, Ferracin, Rajacic, Kaiser, Bernardini, Forrer, Weisser, Elzi, Battegay, Halter, Passweg, Khanna: "Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation and Association With Occurrence and Outcome of Invasive Aspergillosis." in: The Journal of infectious diseases, Vol. 212, Issue 6, pp. 959-67, (2015) (PubMed).

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL17A

Gene ID: 3605, 282863, 100034142