Interferon gamma antibody

Catalog No. ABIN6964014

The Rat Monoclonal anti-Interferon gamma antibody has been validated for Neut. It is suitable to detect Interferon gamma in samples from Mouse. There are 4+ publications available.

Quick Overview for Interferon gamma antibody (ABIN6964014)

Target: Interferon gamma (IFNG)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: Neutralization (Neut)

Clone: R4-6A2

Product Details anti-Interferon gamma Antibody

Specificity: Native and recombinant mouse IFN-γ.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Partially purified mouse IFN-gamma

Isotype: IgG1

Application Details

Application Notes: Neutralization of mouse IFN-γ bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-Interferon gamma antibody (ABIN6964014)

Pettini, Fiorino, Cuppone, Iannelli, Medaglini, Pozzi: "Interferon-γ from Brain Leukocytes Enhances Meningitis by Type 4 Streptococcus pneumoniae." in: Frontiers in microbiology, Vol. 6, pp. 1340, (2015) (PubMed).

Chen, Yan, Kozoriz, Weiner: "Novel CD8+ Treg suppress EAE by TGF-beta- and IFN-gamma-dependent mechanisms." in: European journal of immunology, Vol. 39, Issue 12, pp. 3423-35, (2010) (PubMed).

Sarkar, Cooney, White, Dunlop, Endres, Jorns, Wasco, Fox: "Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4." in: Arthritis research & therapy, Vol. 11, Issue 5, pp. R158, (2010) (PubMed).

Coley, Ford, Hanna, Wagener, Kirk, Larsen: "IFN-gamma dictates allograft fate via opposing effects on the graft and on recipient CD8 T cell responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 1, pp. 225-33, (2009) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFNG

Gene ID: 15978

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy