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C-JUN antibody (AA 231-331) (Alexa Fluor 488)

JUN Reactivity: Human FACS Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN6977745
$470.46
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all C-JUN (JUN) Antibodies
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Binding Specificity
    • 47
    • 41
    • 36
    • 29
    • 29
    • 16
    • 16
    • 16
    • 15
    • 12
    • 11
    • 11
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    AA 231-331
    Reactivity
    • 421
    • 208
    • 189
    • 33
    • 26
    • 21
    • 17
    • 16
    • 16
    • 13
    • 12
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 414
    • 16
    • 2
    Rabbit
    Clonality
    • 393
    • 39
    Polyclonal
    Conjugate
    • 205
    • 25
    • 17
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    This C-JUN antibody is conjugated to Alexa Fluor 488
    Application
    • 243
    • 148
    • 126
    • 120
    • 59
    • 57
    • 47
    • 46
    • 42
    • 26
    • 13
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C-jun
    Isotype
    IgG
  • Application Notes
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    C-JUN (JUN) (Jun Proto-Oncogene (JUN))
    Alternative Name
    C-jun (JUN Products)
    Synonyms
    AP-1 antibody, AP1 antibody, c-Jun antibody, fj36h07 antibody, wu:fj36h07 antibody, zgc:65863 antibody, Junc antibody, c-jun antibody, CG2275 antibody, D-Jun antibody, D-jun antibody, D-jun/Jra antibody, DJUN antibody, DJun antibody, Djun antibody, Dmel\\CG2275 antibody, JRA antibody, JUN antibody, Jun antibody, V antibody, cJun antibody, d-JRA antibody, d-Jun antibody, d-jun antibody, dAP-1 antibody, dJRA antibody, dJUN antibody, dJra antibody, dJun antibody, djun antibody, dm-Jun antibody, jra antibody, jun antibody, l(2)46Ef antibody, l(2)IA109 antibody, l(2R)IA109 antibody, Jun proto-oncogene, AP-1 transcription factor subunit antibody, jun proto-oncogene S homeolog antibody, jun proto-oncogene antibody, Jun-related antigen antibody, jun proto-oncogene L homeolog antibody, JUN antibody, Jun antibody, jun.S antibody, jun antibody, Jra antibody, jun.L antibody
    Background

    The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

    Subcellular location: Nucleus

    Synonyms: Transcription factor AP-1, Jun oncogene, JUN, AP 1, AP1, AP-1, Enhancer Binding Protein AP1, Jun Activation Domain Binding Protein, JUN protein, JUNC, p39, Proto oncogene cJun, Transcription Factor AP1, V jun avian sarcoma virus 17 oncogene homolog, vJun Avian Sarcoma Virus 17 Oncogene Homolog, JUN_HUMAN, Activator 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog.

    Gene ID
    3725
    UniProt
    P05412
    Pathways
    MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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