Myoglobin antibody (AA 2-154) (AbBy Fluor® 488)

Catalog No. ABIN6978073

This Mouse Monoclonal antibody specifically detects Myoglobin in IF (cc) and IF (p). It exhibits reactivity toward Human and Rat.

Quick Overview for Myoglobin antibody (AA 2-154) (AbBy Fluor® 488) (ABIN6978073)

Target: Myoglobin (MB)

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myoglobin antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 3A7

Product Details anti-Myoglobin Antibody (AbBy Fluor® 488)

Binding Specificity: AA 2-154

Cross-Reactivity: Human, Rat

Purification: Purified by Protein G.

Immunogen: Purified Human Myoglobin (Natural Human Myoglobin protein)

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Myoglobin

Target: Myoglobin (MB)

Alternative Name: Myoglobin

Background:

Synonyms: MYO, MB, MGC13548, PVALB, MYG_HUMAN.

Background: Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Gene ID: 4151

UniProt: P02144

Pathways: Brown Fat Cell Differentiation