PIEZO1 + PIEZO2 (AA 2451-2521) antibody (AbBy Fluor® 594)

Catalog No. ABIN6979123

This Rabbit Polyclonal antibody specifically detects in IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for PIEZO1 + PIEZO2 (AA 2451-2521) antibody (AbBy Fluor® 594) (ABIN6979123)

Target: PIEZO1 + PIEZO2

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: AbBy Fluor® 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details

Binding Specificity: AA 2451-2521

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIEZO1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: PIEZO1 + PIEZO2

Background:

Synonyms: Piezo-type mechanosensitive ion channel component 1, Piezo-type mechanosensitive ion channel component 2, PIEZO1, PIEZO2, Mib, C18orf30, C18orf58, FAM38B, FAM38A, KIAA0233

Background: Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types. PIEZO2 Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation

Gene ID: 9780

UniProt: Q92508