GPR75 antibody (AA 151-250) (Cy5.5)

Catalog No. ABIN6985114

This Rabbit Polyclonal antibody specifically detects GPR75 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for GPR75 antibody (AA 151-250) (Cy5.5) (ABIN6985114)

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR75 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GPR75 Antibody (Cy5.5)

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPCR GPR75

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GPR75

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Alternative Name: GPR75

Background:

Synonyms: Probable G-protein coupled receptor 75, GPR75,

Background: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Gene ID: 10936

UniProt: O95800