c-FOS antibody (AA 1-50)
Quick Overview for c-FOS antibody (AA 1-50) (ABIN6989069)
Target
See all c-FOS (c-Fos) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-50
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Cross-Reactivity
- Human
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Predicted Reactivity
- Mouse,Rat
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human c-fos
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Isotype
- IgG
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Application Notes
- IHC-P 1:200-400
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- c-FOS (c-Fos) (c-Fos)
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Alternative Name
- c-fos
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Background
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Synonyms: Cellular oncogene fos, FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus, FOS, FOS protein, G0 G1 switch regulatory protein 7, G0S7, Oncogene FOS, Proto oncogene protein c fos, v fos FBJ murine osteosarcoma viral oncogene homolog, AP-1, p55, FOS_HUMAN, Proto-oncogene c-Fos, G0/G1 switch regulatory protein 7.
Background: Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation.
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Gene ID
- 2353
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UniProt
- P01100
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Pathways
- S100 Proteins
Target
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