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c-FOS antibody (AA 1-50)

The Rabbit Polyclonal anti-c-FOS antibody has been validated for IHC (p). It is suitable to detect c-FOS in samples from Human.
Catalog No. ABIN6989069

Quick Overview for c-FOS antibody (AA 1-50) (ABIN6989069)

Target

See all c-FOS (c-Fos) Antibodies
c-FOS (c-Fos) (c-Fos)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This c-FOS antibody is un-conjugated

Application

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 1-50

    Cross-Reactivity

    Human

    Predicted Reactivity

    Mouse,Rat

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human c-fos

    Isotype

    IgG
  • Application Notes

    IHC-P 1:200-400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    c-FOS (c-Fos) (c-Fos)

    Alternative Name

    c-fos

    Background

    Synonyms: Cellular oncogene fos, FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus, FOS, FOS protein, G0 G1 switch regulatory protein 7, G0S7, Oncogene FOS, Proto oncogene protein c fos, v fos FBJ murine osteosarcoma viral oncogene homolog, AP-1, p55, FOS_HUMAN, Proto-oncogene c-Fos, G0/G1 switch regulatory protein 7.

    Background: Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation.

    Gene ID

    2353

    UniProt

    P01100

    Pathways

    S100 Proteins
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