LGR5 antibody (AA 211-310)

Catalog No. ABIN6989291

The Rabbit Polyclonal anti-LGR5 antibody has been validated for WB, FACS, ELISA, IHC (p), ICC and IHC (fro). It is suitable to detect LGR5 in samples from Human, Mouse and Rat.

Quick Overview for LGR5 antibody (AA 211-310) (ABIN6989291)

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGR5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-LGR5 Antibody

Binding Specificity: AA 211-310

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR49/LGR5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: GPR49/LGR5

Background:

Synonyms: Homing Cell Adhesion Molecule, Epican, Heparan sulfate proteoglycan, Hyaluronate receptor, Antigen gp90 homing receptor, CD44, CD44 antigen, CD44 antigen homing function and Indian blood group system, CD44 Molecule, CD44 Molecule Indian blood group, CD44R, CDw44, CDW44 antigen, Chondroitin sulfate proteoglycan 8, CSPG8, ECMR III, ECMRIII, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCELL, Hematopoietic cell E and L selectin ligand, Hermes antigen, Homing function and Indian blood group system, HUTCH I, IN , INLU related p80 glycoprotein, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH I, MUTCHI, PGP 1, Phagocytic glycoprotein I, CD44_RAT.

Background: Main cell surface receptor for hyaluronate. Adhesion to ucosal high endothelial venule and to types I and VI collagen. robably involved in matrix adhesion, lymphocyte activation and ymph node homing.

Gene ID: 25406

UniProt: O75473

Pathways: WNT Signaling