STK39 antibody

Catalog No. ABIN6989664

This anti-STK39 antibody is a Rabbit Monoclonal antibody detecting STK39 in WB, IHC (p) and FACS. Suitable for Human.

Quick Overview for STK39 antibody (ABIN6989664)

Target: STK39 (serine threonine Kinase 39 (STK39))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STK39 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 6H14

Product Details anti-STK39 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide corresponding to C terminal human SPAK.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for STK39

Target: STK39 (serine threonine Kinase 39 (STK39))

Alternative Name: SPAK

Background:

Synonyms: DCHT antibody, DKFZp686K05124 antibody, OTTHUMP00000165175 antibody, PASK antibody, Proline alanine rich STE20 related kinase antibody, Serine threonine kinase 39 (STE20/SPS1 homolog yeast) antibody, Serine threonine kinase 39 antibody, Serine/threonine protein kinase 39 antibody, Serine/threonine-protein kinase 39 antibody, Small intestine SPAK like kinase antibody, SPAK antibody, Ste 20 related kinase antibody, Ste-20-related kinase antibody, Ste20 like protein kinase antibody, STE20/SPS1 homolog antibody, STE20/SPS1 related proline alanine rich protein kinase antibody, STE20/SPS1-related proline-alanine-rich protein kinase antibody, STK 39 antibody, Stk39 antibody, STK39_HUMAN antibody

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SPAK, also known as STK39 (serine threonine kinase 39), DCHT or PASK, is a 547 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one protein kinase domain. Expressed predominately in pancreas, brain, heart, lung, liver and testis, SPAK functions as a Ser/Thr protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in mediating stress-activated signals. The gene encoding SPAK maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8 % of the human genome.

Gene ID: 27347

UniProt: Q9UEW8