STK17A antibody (N-Term)

Catalog No. ABIN6990303

This anti-STK17A antibody is a Rabbit Polyclonal antibody detecting STK17A in WB, ELISA, ICC and IF. Suitable for Human.

Quick Overview for STK17A antibody (N-Term) (ABIN6990303)

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK17A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-STK17A Antibody

Binding Specificity: N-Term

Specificity: No cross responses to DRAK2, DAP or ZIP kinases.

Purification: DRAK1 Antibody is affinity chromatography purified via peptide column.

Immunogen: DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. The immunogen is located within the first 50 amino acids of DRAK1.

Isotype: IgG

Application Details

Application Notes: DRAK1 antibody can be used for detection of DRAK1 by Western blot at 1 μ,g/mL. An approximately 50 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: DRAK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: DRAK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for STK17A

Target: STK17A (serine/threonine Kinase 17a (STK17A))

Alternative Name: DRAK1

Background: DRAK1 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Molecular Weight: 50 kDa

Gene ID: 9263

UniProt: Q9UEE5