NUP155 antibody (C-Term)

Catalog No. ABIN6990944

The Rabbit Polyclonal anti-NUP155 antibody has been validated for WB and ELISA. It is suitable to detect NUP155 in samples from Human and Mouse.

Quick Overview for NUP155 antibody (C-Term) (ABIN6990944)

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP155 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NUP155 Antibody

Binding Specificity: C-Term

Purification: NUP155 Antibody is affinity chromatography purified via peptide column.

Immunogen: NUP155 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NUP155. The immunogen is located within the last 50 amino acids of NUP155.

Isotype: IgG

Application Details

Application Notes: NUP155 antibody can be used for detection of NUP155 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NUP155 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NUP155 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NUP155

Target: NUP155 (Nucleoporin 155kDa (NUP155))

Alternative Name: NUP155

Background: NUP155 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. One protein in this assembly is the nucleoporin (NUP)-155, which is localized symmetrically to both the nucleoplasmic and cytoplasmic faces of the NPC. NUP155 has been reported to interact with both NUP35 and the mRNA export factor Gle1, but the functions of these interactions are still unknown. NUP155 has also been shown to be required for NPC assembly and nuclear envelope (NE) membrane fusion. NUP155 is recruited late in NE formation, suggesting that NUP155 defines an essential late step in NE assembly. NUP155 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP155 may be an important drug target in HIV treatment. At least two isoforms of NUP155 are known to exist.

Gene ID: 9631

NCBI Accession: NP_705618

UniProt: O75694

Pathways: Protein targeting to Nucleus