GP120 antibody (AA 470-520)

Catalog No. ABIN6990968

The Goat Polyclonal anti-GP120 antibody has been validated for ELISA and WB. It is suitable to detect GP120 in samples from Human Immunodeficiency Virus (HIV).

Quick Overview for GP120 antibody (AA 470-520) (ABIN6990968)

Target: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Goat

Clonality: Polyclonal

Conjugate: This GP120 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-GP120 Antibody

Binding Specificity: AA 470-520

Purification: gp120 Antibody is affinity chromatography purified via peptide column.

Immunogen: gp120 antibody was raised against 15 amino acids from near the center of gp120. The immunogen is located within amino acids 470 - 520 of gp120.

Isotype: IgG

Application Details

Application Notes: Gp120 antibody can be used for detection of gp120 by Western blot at 1 µg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: gp120 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: gp120 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GP120

Target: GP120 (HIV-1 gp120) (Human Immunodeficiency Virus 1 Surface Glycoprotein (HIV-1 gp120))

Alternative Name: HIV1 Gp120

Target Type: Viral Protein

Background: Gp120 Antibody: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Gene ID: 155971

UniProt: Q6BBS3