MATN2 antibody (C-Term)

Catalog No. ABIN6991088

The Rabbit Polyclonal anti-MATN2 antibody has been validated for WB and ELISA. It is suitable to detect MATN2 in samples from Human, Mouse and Rat.

Quick Overview for MATN2 antibody (C-Term) (ABIN6991088)

Target: MATN2 (Matrilin 2 (MATN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MATN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MATN2 Antibody

Binding Specificity: AA 820-870, C-Term

Purification: MATN2 Antibody is affinity chromatography purified via peptide column.

Immunogen: MATN2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human MATN2. The immunogen is located within amino acids 820 - 870 of MATN2.

Isotype: IgG

Application Details

Application Notes: MATN2 antibody can be used for detection of MATN2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MATN2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MATN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MATN2

Target: MATN2 (Matrilin 2 (MATN2))

Alternative Name: MATN2

Background: MATN2 Antibody: Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.

Molecular Weight: Predicted: 102 kDa

Observed: 105 kDa

Gene ID: 4147

NCBI Accession: NP_085072

UniProt: O00339