LRRC19 antibody (C-Term)

Catalog No. ABIN6991292

The Rabbit Polyclonal anti-LRRC19 antibody has been validated for ELISA, WB, IF and ICC. It is suitable to detect LRRC19 in samples from Human and Mouse.

Quick Overview for LRRC19 antibody (C-Term) (ABIN6991292)

Target: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC19 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-LRRC19 Antibody

Binding Specificity: AA 290-340, C-Term

Purification: LRRC19 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRRC19 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRC19. The immunogen is located within amino acids 290 - 340 of LRRC19.

Isotype: IgG

Application Details

Application Notes: LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRC19 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LRRC19 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LRRC19

Target: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Alternative Name: LRRC19

Background: LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κ,B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

Gene ID: 64922

NCBI Accession: NP_075052

UniProt: Q9H756