USP10 antibody (N-Term)

Catalog No. ABIN6991355

The Rabbit Polyclonal anti-USP10 antibody has been validated for WB, IF, ELISA and ICC. It is suitable to detect USP10 in samples from Human and Mouse.

Quick Overview for USP10 antibody (N-Term) (ABIN6991355)

Target: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Product Details anti-USP10 Antibody

Binding Specificity: AA 30-80, N-Term

Purification: USP10 Antibody is affinity chromatography purified via peptide column.

Immunogen: USP10 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human USP10. The immunogen is located within amino acids 30 - 80 of USP10.

Isotype: IgG

Application Details

Application Notes: USP10 antibody can be used for detection of USP10 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: USP10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: USP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for USP10

Target: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Alternative Name: USP10

Background: USP10 Antibody: USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.

Gene ID: 9100

NCBI Accession: NP_005144

UniProt: Q14694