TMEM204 antibody (C-Term)

Catalog No. ABIN6991560

This anti-TMEM204 antibody is a Rabbit Polyclonal antibody detecting TMEM204 in WB, ELISA, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for TMEM204 antibody (C-Term) (ABIN6991560)

Target: TMEM204 (Transmembrane Protein 204 (TMEM204))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM204 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TMEM204 Antibody

Binding Specificity: C-Term

Specificity: At least two isoforms of TMEM204 are known to exist, this antibody will recognize both isoforms.

Purification: TMEM204 Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM204 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TMEM204. The immunogen is located within the last 50 amino acids of TMEM204.

Isotype: IgG

Application Details

Application Notes: TMEM204 antibody can be used for detection of TMEM204 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM204 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TMEM204 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TMEM204

Target: TMEM204 (Transmembrane Protein 204 (TMEM204))

Alternative Name: TMEM204

Background: TMEM204 Antibody: Transmembrane protein 204 (TMEM204) is a four-transmembrane protein that is induced under hypoxic conditions. It localizes to cell-cell junctions and co-localizes with the beta-catenin adherens junction-associated protein, but not with tight junctions. Overexpression of TMEM204 results in decreased adhesion between cells, indicating that TMEM204 is an adherens junction protein that modulates cell adhesion and potentially angiogenesis. Recent evidence suggests TMEM204 may also be involved in epilepsy.

Gene ID: 79652

NCBI Accession: NP_078876

UniProt: Q9BSN7