TMEM106B antibody (N-Term)

Catalog No. ABIN6991669

Product Details anti-TMEM106B Antibody

Target: TMEM106B (Transmembrane Protein 106B (TMEM106B))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM106B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This TMEM106B antibody is predicted to have no cross-reactivity to TMEM106A.

Purification: TMEM106B Antibody is affinity chromatography purified via peptide column.

Immunogen: TMEM106B antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TMEM106B. The immunogen is located within the first 50 amino acids of TMEM106B.

Isotype: IgG

Application Details

Application Notes: TMEM106B antibody can be used for detection of TMEM106B by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM106B Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TMEM106B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TMEM106B

Target: TMEM106B (Transmembrane Protein 106B (TMEM106B))

Alternative Name: TMEM106B (TMEM106B Products)

Background: TMEM106B Antibody: Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.

Molecular Weight: Predicted: 30 kDa

Observed: 33 kDa

Gene ID: 54664

NCBI Accession: NP_060844

UniProt: Q9NUM4