Septin 1 antibody (C-Term)

Catalog No. ABIN6991703

The Rabbit Polyclonal anti-Septin 1 antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect Septin 1 in samples from Human, Mouse and Rat.

Quick Overview for Septin 1 antibody (C-Term) (ABIN6991703)

Target: Septin 1 (SEPT1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Septin 1 Antibody

Binding Specificity: AA 300-350, C-Term

Specificity: At least two isoforms of SEPT1 are known to exist. This antibody is predicted to not cross-react with other Septin protein family members.

Purification: SEPT1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SEPT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SEPT1. The immunogen is located within amino acids 300 - 350 of SEPT1.

Isotype: IgG

Application Details

Application Notes: SEPT1 antibody can be used for detection of SEPT1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SEPT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SEPT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Septin 1

Target: Septin 1 (SEPT1)

Alternative Name: SEPT1

Background: SEPT1 Antibody: SEPT1 (also known as Septin 1), is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. SEPT1 was initially identified through yeast two-hybrid screening as an interaction partner for the serine/threonine kinase Aurora-B. During mitosis, SEPT1 localizes to the spindle pole, suggesting that it may play a role in cytokinesis and chromosome congression.

Gene ID: 1731

NCBI Accession: NP_443070

UniProt: Q8WYJ6