TLX1 antibody (N-Term)

Catalog No. ABIN6991866

This anti-TLX1 antibody is a Rabbit Polyclonal antibody detecting TLX1 in WB, ELISA and IHC (p). Suitable for Mouse, Human and Rat.

Quick Overview for TLX1 antibody (N-Term) (ABIN6991866)

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TLX1 Antibody

Binding Specificity: N-Term

Specificity: Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.

Purification: TLX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: TLX1 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX1. The immunogen is located within the first 50 amino acids of TLX1.

Isotype: IgG

Application Details

Application Notes: TLX1 antibody can be used for detection of TLX1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TLX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TLX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TLX1

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Alternative Name: TLX1

Background: TLX1 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.

Molecular Weight: Predicted: 36 kDa

Observed: 35 kDa

Gene ID: 3195

NCBI Accession: NP_005512

UniProt: P31314