AJAP1 antibody (C-Term)

Catalog No. ABIN6992131

This Rabbit Polyclonal antibody specifically detects AJAP1 in WB, ELISA and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AJAP1 antibody (C-Term) (ABIN6992131)

Target: AJAP1 (Adherens Junctions Associated Protein 1 (AJAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AJAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-AJAP1 Antibody

Binding Specificity: AA 290-340, C-Term

Specificity: AJAP1 antibody is human, mouse and rat reactive.

Purification: AJAP1 antibody is affinity chromatography purified via peptide column.

Immunogen: AJAP1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human AJAP1. The immunogen is located within amino acids 290 - 340 of AJAP1.

Isotype: IgG

Application Details

Application Notes: AJAP1 antibody can be used for detection of AJAP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: AJAP1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: AJAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for AJAP1

Target: AJAP1 (Adherens Junctions Associated Protein 1 (AJAP1))

Alternative Name: AJAP1

Background: The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1). It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1,2). AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3). This facilitates the dissolution of adherens junctions with an increase in cell motility (3,4).

Molecular Weight: Predicted: 45 kDa

Observed: 48 kDa

Gene ID: 55966

NCBI Accession: NP_061324

UniProt: Q9UKB5