S1PR2 antibody (C-Term)

Catalog No. ABIN6992153

The Rabbit Polyclonal anti-S1PR2 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect S1PR2 in samples from Human, Mouse and Rat.

Quick Overview for S1PR2 antibody (C-Term) (ABIN6992153)

Target: S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S1PR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-S1PR2 Antibody

Binding Specificity: AA 270-320, C-Term

Specificity: S1PR2 antibody is human, mouse and rat reactive.

Purification: S1PR2 antibody is affinity chromatography purified via peptide column.

Immunogen: S1PR2 antibody was raised against an 16 amino acid peptide near the carboxy terminus of human S1PR2. The immunogen is located within amino acids 270 - 320 of S1PR2.

Isotype: IgG

Application Details

Application Notes: S1PR2 antibody can be used for detection of S1PR2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: S1PR2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: S1PR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for S1PR2

Target: S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))

Alternative Name: S1PR2

Background: The Sphingosine 1-phosphate receptor 2 (S1PR2) protein was initially identified as G-protein coupled receptor thought to be involved in development (1) and was found to mediate sphingosine 1-phosphate (SPP)-induced cell rounding and neurite retraction (2). S1PR2 and the related protein S1PR3 (also known as EDG3) are also thought to mediate the SPP-induced cell proliferation, survival, and related signaling events (3). S1PR2 has also been found to be key regulator in acute vascular inflammation and may be a novel therapeutic target for vascular disorders (4).

Molecular Weight: Predicted: 39 kDa

Observed: 50 kDa

Gene ID: 9294

NCBI Accession: NP_004221

UniProt: O95136

Pathways: Synaptic Membrane