C9ORF72 antibody (C-Term)

Catalog No. ABIN6992180

The Rabbit Polyclonal anti-C9ORF72 antibody has been validated for WB, ELISA and ICC. It is suitable to detect C9ORF72 in samples from Human, Rat and Mouse.

Quick Overview for C9ORF72 antibody (C-Term) (ABIN6992180)

Target: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9ORF72 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-C9ORF72 Antibody

Binding Specificity: AA 400-450, C-Term

Specificity: ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.

Purification: ALSFTD Antibody is affinity chromatography purified via peptide column.

Immunogen: ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD.

Isotype: IgG

Application Details

Application Notes: ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ALSFTD Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ALSFTD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for C9ORF72

Target: C9ORF72 (Chromosome 9 Open Reading Frame 72 (C9ORF72))

Alternative Name: ALSFTD

Background: ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).

Molecular Weight: Predicted: 53 kDa

Observed: 52 kDa

Gene ID: 203228

NCBI Accession: NP_060795

UniProt: Q96LT7