SARS-CoV-2 NSP16 antibody (AA 120-170)

Catalog No. ABIN6992287

This Rabbit Polyclonal antibody specifically detects SARS-CoV-2 NSP16 in ELISA, WB and IHC. It exhibits reactivity toward SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for SARS-CoV-2 NSP16 antibody (AA 120-170) (ABIN6992287)

Target: SARS-CoV-2 NSP16 (NSP16) (SARS-CoV-2 2'-O-Ribose Methyltransferase (NSP16))

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS-CoV-2 NSP16 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SARS-CoV-2 NSP16 Antibody

Binding Specificity: AA 120-170

Purification: SARS-CoV-2 (COVID-19) NSP16 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) NSP16 antibody was raised against a peptide corresponding to 16 amino acids near the central domain of SARS-CoV-2 (COVID-19) NSP16 protein. The immunogen is located within 120-170 amino acids of the SARS-CoV-2 (COVID-19) NSP16 protein.

Isotype: IgG

Application Details

Application Notes: IHC: 0.5 μ,g/mL, WB: 0.5 μ,g/mL

Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP16 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 NSP16 recombinant protein by ELISA and WB. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) NSP16 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SARS-CoV-2 (COVID-19) NSP16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SARS-CoV-2 NSP16

Target: SARS-CoV-2 NSP16 (NSP16) (SARS-CoV-2 2'-O-Ribose Methyltransferase (NSP16))

Alternative Name: SARS-CoV-2 NSP16

Target Type: Viral Protein

Background: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Methyltransferase mediates mRNA cap 2'-O-ribose methylation to the 5'-cap structure of viral mRNAs. N7-methyl guanosine cap is a prerequisite for binding of nsp16. Therefore plays an essential role in viral mRNAs cap methylation which is essential to evade immune system.

Gene ID: 43740578

NCBI Accession: YP_009725311

UniProt: P0DTC1