ENPP7 antibody

Catalog No. ABIN7000956

The Rabbit Polyclonal anti-ENPP7 antibody has been validated for WB, IHC and ELISA. It is suitable to detect ENPP7 in samples from Human and Rat.

Quick Overview for ENPP7 antibody (ABIN7000956)

Target: ENPP7 (Alkaline Sphingomyelinase (Alk-Smase))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ENPP7 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human ENPP7

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ENPP7

Target: ENPP7 (Alkaline Sphingomyelinase (Alk-Smase))

Alternative Name: ENPP7

Background: Ectonucleotide pyrophosphatase/phosphodiesterase family member 7(E-NPP 7) also known asalkaline sphingomyelin phosphodiesterase(Alk-SMase) orintestinal alkaline sphingomyelinaseis anenzymethat in humans is encoded by theENPP7gene. Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity. Inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Not inhibited by ADP, AMP and EDTA. Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.

Molecular Weight: 52 kDa

NCBI Accession: NP_848638

UniProt: Q6UWV6