ITPR2 antibody
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- Target See all ITPR2 Antibodies
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ITPR2 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human ITPR2
- Isotype
- IgG
- Top Product
- Discover our top product ITPR2 Primary Antibody
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anti-Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) (Internal Region) antibody
Verified ITPR2 Reactivity: Human IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) antibodyITPR2 Reactivity: Human, Rat, Mouse IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) (AA 2683-2696), (C-Term), (Intracellular) antibodyITPR2 Reactivity: Rat IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) (N-Term) antibodyITPR2 Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2) (AA 2683-2696), (C-Term), (Intracellular) antibody (Atto 594)ITPR2 Reactivity: Rat IHC, IF Host: Rabbit Polyclonal Atto 594
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.9 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
- Alternative Name
- ITPR2 (ITPR2 Products)
- Background
- Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
- NCBI Accession
- NP_002214
- UniProt
- Q14571
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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