ITPR2 antibody (C-Term)

Catalog No. ABIN228640

Product Details anti-ITPR2 Antibody

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Monkey, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPR2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Directed against a synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor. Species cross-reactivity: Human, mouse, hamster and monkey.

Purification: Affinity purified

Immunogen: Synthetic peptide corresponding to the carboxy terminus of the rat Type II receptor.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ICC, IF (1:10 - 1:20), IHC, IP, WB (1:50 - 1:100)

Usage: Suitable for use in Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. Western Blot: 1:50-1:100 (detects a 260kD band). Immunofluorescence: 1:10-1:20. Immunohistochemistry: Paraformaldehyde or methanol fixed sections. Immunocytochemistry: Known to give positive reactivity on AR4-2J, HL-60, COS-I, HEK-293 and RBL-2H3 cell lines.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % BSA, 0.005 % sodium azide, 10 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ITPR2

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Alternative Name: ITPR2 / IP3 Receptor Type 2 (ITPR2 Products)

Synonyms: AI649341 antibody, InsP3R-2 antibody, InsP3R-5 antibody, Ip3r2 antibody, Itpr5 antibody, insP3R2 antibody, IP3R2 antibody, inositol 1,4,5-trisphosphate receptor type 2 antibody, inositol 1,4,5-triphosphate receptor 2 antibody, inositol 1,4,5-trisphosphate receptor, type 2 antibody, ITPR2 antibody, Itpr2 antibody

Background: Name/Gene ID: ITPR2
Subfamily: Inositol 1,4,5-triphosphate receptor
Family: Ion Channel

Synonyms: ITPR2, IP3R 2, InsP3R2, IP3R2, InsP3R type II, IP3 receptor, InsP3R type 2, IP3 receptor isoform 2, Type 2 InsP3 receptor

Gene ID: 3709

UniProt: Q14571

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma