ITPR2 antibody (N-Term)

Catalog No. ABIN2776138

Product Details anti-ITPR2 Antibody

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPR2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FRDCLFKVCP MNRYSAQKQY WKAKQAKQGN HTEAALLKKL QHAAELEQKQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ITPR2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN ITPR2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ITPR2

Target: ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))

Alternative Name: ITPR2 (ITPR2 Products)

Synonyms: AI649341 antibody, InsP3R-2 antibody, InsP3R-5 antibody, Ip3r2 antibody, Itpr5 antibody, insP3R2 antibody, IP3R2 antibody, inositol 1,4,5-trisphosphate receptor type 2 antibody, inositol 1,4,5-triphosphate receptor 2 antibody, inositol 1,4,5-trisphosphate receptor, type 2 antibody, ITPR2 antibody, Itpr2 antibody

Background: ITPR2 is a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA.
Protein Interaction Partner: UBC, TRPC1, BANK1, TRPC4, PRKACA,
Protein Size: 181

Molecular Weight: 19 kDa

Gene ID: 3709

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma