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STK40 antibody

This Rabbit Polyclonal antibody specifically detects STK40 in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7240700
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$457.98
$538.80
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Quick Overview for STK40 antibody (ABIN7240700)

Target

See all STK40 Antibodies
STK40 (serine/threonine Kinase 40 (STK40))

Reactivity

  • 23
  • 19
  • 18
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Mouse, Rat

Host

  • 33
  • 5
Rabbit

Clonality

  • 36
  • 2
Polyclonal

Conjugate

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STK40 antibody is un-conjugated

Application

  • 30
  • 13
  • 13
  • 8
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant protein of human STK40

    Isotype

    IgG
  • Application Notes

    IHC 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.3 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    STK40 (serine/threonine Kinase 40 (STK40))

    Alternative Name

    STK40

    Background

    STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

    UniProt

    Q8N2I9
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