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STK40 antibody

This Rabbit Polyclonal antibody specifically detects STK40 in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7240700

Quick Overview for STK40 antibody (ABIN7240700)

Target

See all STK40 Antibodies
STK40 (serine/threonine Kinase 40 (STK40))

Reactivity

  • 23
  • 19
  • 18
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Mouse, Rat

Host

  • 33
  • 5
Rabbit

Clonality

  • 36
  • 2
Polyclonal

Conjugate

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STK40 antibody is un-conjugated

Application

  • 30
  • 13
  • 13
  • 8
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant protein of human STK40

    Isotype

    IgG
  • Application Notes

    IHC 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.3 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    STK40 (serine/threonine Kinase 40 (STK40))

    Alternative Name

    STK40

    Background

    STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

    UniProt

    Q8N2I9
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