CATSPER3 antibody

Catalog No. ABIN7002044

This Rabbit Polyclonal antibody specifically detects CATSPER3 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for CATSPER3 antibody (ABIN7002044)

Target: CATSPER3 (Cation Channel, Sperm Associated 3 (CATSPER3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CATSPER3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CATSPER3 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CATSPER3

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CATSPER3

Target: CATSPER3 (Cation Channel, Sperm Associated 3 (CATSPER3))

Alternative Name: CATSPER3

Background: CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. Mutations in any of the genes encoding CatSper family proteins can result in male infertility. CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.

Molecular Weight: 46 kDa

UniProt: Q86XQ3