MCTS1 antibody

Catalog No. ABIN7241675

This Rabbit Polyclonal antibody specifically detects MCTS1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for MCTS1 antibody (ABIN7241675)

Target: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCTS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MCTS1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human MCTS1

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000, IHC 1:100-1:300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MCTS1

Target: MCTS1 (Malignant T Cell Amplified Sequence 1 (MCTS1))

Alternative Name: MCTS1

Background: MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.

Molecular Weight: 21 kDa

UniProt: Q9ULC4