C16orf45 antibody

Catalog No. ABIN7244585

This Rabbit Polyclonal antibody specifically detects C16orf45 in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for C16orf45 antibody (ABIN7244585)

Target: C16orf45 (Chromosome 16 Open Reading Frame 45 (C16orf45))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C16orf45 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-C16orf45 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human C16orf45

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C16orf45

Target: C16orf45 (Chromosome 16 Open Reading Frame 45 (C16orf45))

Alternative Name: C16orf45

Background: C16orf45, also known as FLJ32618, is a 204 amino acid protein encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

UniProt: Q96MC5