IL-24 antibody

Catalog No. ABIN7244849

The Rabbit Polyclonal anti-IL-24 antibody has been validated for IHC and ELISA. It is suitable to detect IL-24 in samples from Human.

Quick Overview for IL-24 antibody (ABIN7244849)

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-24 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-IL-24 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human IL24

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Alternative Name: IL24

Background: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.IL24 (Interleukin 24) is a Protein Coding gene. Diseases associated with IL24 include Melanoma and Subclavian Steal Syndrome. Among its related pathways are PEDF Induced Signaling and Immune response IL-23 signaling pathway. GO annotations related to this gene include cytokine activity. An important paralog of this gene is IL20.

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy