Lamin B1 antibody

Catalog No. ABIN7245590

This anti-Lamin B1 antibody is a Rabbit Polyclonal antibody detecting Lamin B1 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Lamin B1 antibody (ABIN7245590)

Target: Lamin B1 (LMNB1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Lamin B1 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human LMNB1

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: LMNB1

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 67 kDa

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis