GCAT antibody
Quick Overview for GCAT antibody (ABIN7246613)
Target
See all GCAT AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of human GCAT
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.02 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GCAT (Glycine C-Acetyltransferase (GCAT))
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Alternative Name
- GCAT
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Background
- The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 45 kDa
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UniProt
- O75600
Target
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