IDS antibody
Quick Overview for IDS antibody (ABIN7247726)
Target
See all IDS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of human IDS
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Isotype
- IgG
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Application Notes
- IHC 1:50-1:200, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.02 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- IDS (Iduronate 2-Sulfatase (IDS))
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Alternative Name
- IDS
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Background
- Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome,an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide..
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UniProt
- P22304
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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