PROC
Reactivity: Human
ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC 1:100-1:300, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
3 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
PROC
(Vitamin K-dependent protein C (PROC))
Alternative Name
PROC
Background
This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]