The Rabbit Polyclonal anti-Calsequestrin antibody has been validated for ELISA and IHC. It is suitable to detect Calsequestrin in samples from Human, Mouse and Rat.
CASQ1
Reactivity: Human
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC 1:50-1:300, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
1.6 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
Calsequestrin (CASQ1)
(Calsequestrin 1 (CASQ1))
Alternative Name
CASQ1
Background
This gene encodes the skeletal muscle specific member of the calsequestrin protein family. Calsequestrin functions as a luminal sarcoplasmic reticulum calcium sensor in both cardiac and skeletal muscle cells. This protein, also known as calmitine, functions as a calcium regulator in the mitochondria of skeletal muscle. This protein is absent in patients with Duchenne and Becker types of muscular dystrophy.