The Rabbit Polyclonal anti-xpr1 antibody (ABIN7254235) specifically detects xpr1 in ELISA and IHC.
The antibody is reactive with Human and Mouse samples.
xpr1
Reactivity: Human
ELISA, WB
Host: Rabbit
Polyclonal
PE
Application Notes
IHC 1:50-1:200, ELISA 1:1000-1:5000
Restrictions
For Research Use only
Format
Liquid
Concentration
1.73 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
xpr1
(Xenotropic and Polytropic Retrovirus Receptor 1 (xpr1))
Alternative Name
XPR1
Background
Xenotropic mouse leukemia viruses (X-MLVs) are broadly infectious for mammals except most of the classical strains of laboratory mice. These gammaretroviruses rely on the XPR1 receptor for entry, and the unique resistance of laboratory mice is due to two mutations in different putative XPR1extracellular loops. Cells from avian species differ in susceptibility to X-MLVs, and 2 replacement mutations in the virus-resistant chicken XPR1 distinguish it from the more permissive duck and quail receptors.