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BRI3BP antibody

The Rabbit Polyclonal anti-BRI3BP antibody has been validated for WB, ELISA and IHC. It is suitable to detect BRI3BP in samples from Human and Mouse.
Catalog No. ABIN7254535

Quick Overview for BRI3BP antibody (ABIN7254535)

Target

See all BRI3BP Antibodies
BRI3BP (BRI3 Binding Protein (BRI3BP))

Reactivity

  • 39
  • 12
  • 2
  • 2
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  • 1
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  • 1
Human, Mouse

Host

  • 38
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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This BRI3BP antibody is un-conjugated

Application

  • 17
  • 16
  • 13
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  • 4
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Characteristics

    Polyclonal Antibody

    Purification

    Antigen affinity purification

    Immunogen

    Synthetic peptide of human BRI3BP

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.9 mg/mL

    Buffer

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    BRI3BP (BRI3 Binding Protein (BRI3BP))

    Alternative Name

    BRI3BP

    Background

    BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.

    Molecular Weight

    Observed_MW: Refer to figures

    Calculated_MW: 28 kDa

    UniProt

    Q8WY22
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